Peter Carlen

Peter Carlen

BIOGRAPHY

Peter L. Carlen MD, FRCPC, obtained his MD from the University of Toronto and his internship and Internal Medicine training at McGill University, completing his Neurology training at the University of Toronto. He also did postgraduate training in cellular electrophysiology for 3 years at the Neurobiology Unit of the Hebrew University of Jerusalem, Israel. He is a Professor in Medicine (Neurology), Physiology, and the Institute of Biomaterials and Biomedical Engineering at the University of Toronto. He was formerly the Head of Neurology at the Addiction Research Foundation. In 1989, he was appointed Director of the Playfair Neuroscience Unit and Neuroscience Research at the University Health Network for a 10 year term, where he is now a Senior Scientist and Head of the Division of Fundamental Neurobiology. He has over 300 peer-reviewed biomedical publications and 6 patents. His main research interests are mechanisms and control of neural synchrony and entrainment in epilepsy, SUDEP, hypoglycemic seizures, gap junctional communication, brain state classification, and the cerebral pathophysiology of the fetal alcohol syndrome. He is also an active neurological clinician at the University Health Network (Toronto Western Hospital) with a practice focused mainly on patients with epilepsy.

RESEARCH INTERESTS

Membrane and synaptic properties of mammalian CNS neurons/glia; Physiological, pharmacological and pathological studies of seizure disorders, hypoglycemia, and fetal alcohol spectrum disorder, using electrophysical recordings, imaging and molecular biological techniques from in vitro and in vivo brain tissue; brain state classification and brain stimulation paradigms in animal models and humans; machine learning of human EEG in epilepsy patients for seizure prediction, drug efficacy, and assessing risk of sudden unexplained death (SUDEP).